Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI4B12), TrueMAB
CAMK2B 단백질을 인식하는 마우스 단클론 항체로 인간, 마우스, 랫트에 반응합니다. Western blot에 최적화되어 있으며, 보존제 없는 PBS 버퍼에 동결건조 형태로 제공됩니다. 신경계 연구 및 단백질 발현 분석에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–385 of human CAMK2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, vesicle mobilization, and gene expression regulation.
It functions prominently in the central nervous system, contributing to long-term potentiation and neurotransmitter release.
Four CaMKII isozymes (alpha, beta, gamma, delta) may be co-expressed in various tissues.
CaMKII alpha undergoes autophosphorylation on Thr286 upon Ca²⁺/CaM binding, a process known as Ca²⁺/CaM trapping, associated with synaptic information encoding.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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