Thermo Fisher Scientific RPSA Polyclonal Antibody
Thermo Fisher Scientific의 RPSA Polyclonal Antibody는 인간, 마우스, 원숭이, 랫트에서 반응하며, Western blot 및 IHC(P) 실험에 적합한 고품질 Rabbit IgG 항체입니다. 67kDa Laminin Receptor를 검출하며, 액상 형태로 -20°C에서 보관합니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPSA (Accession P08865), corresponding to amino acid residues V245–S295 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899431 |
Product Specific Information
This antibody detects endogenous levels of total 67kDa Laminin Receptor.
Target Information
Laminins are extracellular matrix glycoproteins forming the major noncollagenous component of basement membranes. They play key roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminin effects are mediated through integrin and non-integrin laminin-binding receptors.
The RPSA gene encodes a high-affinity, non-integrin laminin receptor (67 kD laminin receptor / 37 kD laminin receptor precursor / p40 ribosome-associated protein). Its sequence is highly conserved, and expression is elevated in certain cancer tissues, correlating with invasive and metastatic phenotypes. Multiple pseudogenes exist due to retropositional events, and two alternatively spliced transcripts encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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