Thermo Fisher Scientific ZFPM1 Polyclonal Antibody
ZFPM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며 Western blot에 적합. 고순도 Affinity chromatography로 정제되어 1 mg/mL 농도로 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ZFPM1 (Accession Q8IX07), corresponding to amino acid residues A651–H701 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899427 |
Product Specific Information
Antibody detects endogenous levels of total ZFPM1.
Target Information
ZFPM1 is a transcription regulator essential for erythroid and megakaryocytic cell differentiation. It functions as a cofactor by forming heterodimers with GATA family transcription factors (GATA1, GATA2, GATA3), which can either activate or repress transcription depending on the cellular and promoter context. These heterodimers are crucial for activating genes such as NFE2, ITGA2B, alpha- and beta-globin, and repressing KLF1. ZFPM1 may also regulate genes in gonads and play a role in cardiac development alongside ZFPM2/FOG2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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