Thermo Fisher Scientific TGFBI Monoclonal Antibody (OTI9A11), TrueMAB
TGFBI 단백질을 표적하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 세포-콜라겐 상호작용 연구 및 TGF-β 관련 기능 분석에 적합.
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Applications
- Western Blot (WB): 1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–683 of human TGFBI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of ~1 mg/mL.
- For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes an RGD-containing protein that binds to type I, II, and IV collagens.
The RGD motif, found in many extracellular matrix proteins, modulates cell adhesion and serves as a ligand recognition sequence for several integrins.
This protein plays a role in cell–collagen interactions and may be involved in endochondrial bone formation in cartilage.
It is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
Mutations in this gene are associated with multiple types of corneal dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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