
Thermo Fisher Scientific beta Synuclein Polyclonal Antibody
beta Synuclein 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin)에 적합합니다. Human 및 Mouse 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 93–122 amino acids from the C-terminal region of human SNCB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543238 |
Target Information
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been implicated in major diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and breast cancer.
In AD, a peptide derived from alpha synuclein forms part of plaque amyloid; in PD, alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to familial cases of PD. In breast cancer, increased expression of gamma synuclein correlates with disease progression. Synucleins also appear to be involved in membrane plasticity in the developing song control system of songbirds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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