Thermo Fisher Scientific GM2A Polyclonal Antibody
Rabbit polyclonal antibody targeting human GM2A protein. Validated for Western blot at 1:1,000 dilution. Predicted cross-reactivity with non-human primates. Supplied as liquid, unconjugated form. Suitable for research use only.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 25–54 amino acids of human GM2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543237 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
This gene encodes a small glycolipid transport protein acting as a substrate-specific cofactor for the lysosomal enzyme beta-hexosaminidase A. Together with GM2 ganglioside activator, it catalyzes degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines.
Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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