Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Rabbit polyclonal antibody targeting Contactin 2 (CNTN2) for WB and IHC applications. Reacts with human and mouse, predicted to react with rat. High purity via Protein A and antigen affinity chromatography. Supplied as 0.5 mg/mL liquid in PBS with sodi...
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 293–321 amino acids from the central region of human CNTN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543242 |
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system.
It is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin-like and four fibronectin type III-like domains.
Contactin 2 is expressed predominantly during neural development on axonal membranes to guide commissural axons without promoting their growth.
It binds with NgCAM in cis on the same membrane, and heterophilic binding (Contactin 2/NgCAM and Contactin 2/NrCAM) sites are localized to the first four Ig domains, while homophilic (Contactin 2/Contactin 2) binding sites are localized to the FNIII domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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