
Thermo Fisher Scientific NR2E3 Monoclonal Antibody (OTI1D3), TrueMAB
인간 NR2E3 단백질에 특이적인 마우스 단클론 항체로, Western blot에 최적화됨. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 액상 형태로 1 mg/mL 농도, -20°C에서 안정적 보관 가능. 연구용으로 시각세포 발달 및 망막 관련 연구에 적합.
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- TA806269
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Full length human recombinant protein of human NR2E3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It plays a role in determining photoreceptor phenotype during human retinogenesis.
In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration.
A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte.
Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina.
ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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