
Thermo Fisher Scientific NR0B2 Monoclonal Antibody (OTI1A2), TrueMAB
NR0B2 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot에 최적화된 TrueMAB 형식의 항체. Human 시료에 반응하며, 고순도 Affinity chromatography로 정제됨. 안정한 액상 형태로 -20°C 보관.
- 카탈로그번호
- TA806268
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human NR0B2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by NR0B2 is an orphan nuclear receptor with a ligand-binding domain but lacking a conventional DNA-binding domain. It belongs to the nuclear hormone receptor family, which includes transcription factors regulated by small hydrophobic hormones. NR0B2 interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. It represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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