Thermo Fisher Scientific Cardiac Troponin C Monoclonal Antibody (1A2)
Cardiac Troponin C 단백질을 인식하는 Mouse monoclonal antibody (Clone 1A2). Western blot, ELISA, Affinity Purification에 사용 가능. 2 mg/mL 액상 형태, 4°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| ELISA | Assay-dependent |
| Affinity Purification (AP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A2 |
| Immunogen | Isolated slow skeletal isoform of TnC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2240780 |
Product Specific Information
MA1-22697 detects Cardiac Troponin C in human samples.
Target Information
Troponin (Tn) is the central regulatory protein of striated muscle contraction.
It consists of three components:
- Tn-I: Inhibitor of actomyosin ATPase
- Tn-T: Contains the binding site for tropomyosin
- Tn-C: Binds calcium ions
The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. As calcium ions are taken up by troponin-C, the thin filament undergoes allosteric changes that enable actin–myosin interaction, ATP hydrolysis, and tension generation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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