Thermo Fisher Scientific Phospho-EphA1 (Tyr781) Polyclonal Antibody
인간 및 마우스 반응성을 가진 Rabbit Polyclonal 항체로, EphA1의 Tyr781 인산화 형태를 특이적으로 검출. Western blot에 1:1,000~1:3,000 희석으로 사용 가능. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA1 (Accession P21709), corresponding to amino acid residues around phosphorylated Tyr781 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817524 |
Product Specific Information
Antibody detects endogenous levels of EPHA1 only when phosphorylated at Tyr781.
Target Information
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors are involved in developmental processes, particularly in the nervous system. These receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats. Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand-binding affinity (ephrin-A and ephrin-B). EphA1 is expressed in certain human cancer cell lines and has been implicated in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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