Thermo Fisher Scientific Phospho-EphA6 (Tyr978) Polyclonal Antibody
인간, 생쥐, 랫트에서 인산화 Tyr978 위치의 EphA6 단백질을 검출하는 Rabbit Polyclonal 항체. Western blot에 최적화된 고순도 항체로, 신경계 연구 및 인산화 단백질 분석에 적합. 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA6 (Accession Q9UF33), corresponding to amino acid residues around phosphorylated Tyr978 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817528 |
Product Specific Information
Antibody detects endogenous levels of EPHA6 only when phosphorylated at Tyr978.
Target Information
EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in the nervous system.
EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia.
Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-106130_EphA6_Q9UF33-1_Rabbit_PDP.jpeg)
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