Thermo Fisher Scientific Phospho-EphA6 (Tyr978) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human EPHA6(Accession Q9UF33), corresponding to amino acid residues around phosphorylated Tyr978. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EphA6,uniProtId:Q9UF33-1,ncbiNodeId:9606,antigenRange:978,antigenLength:1036,antigenImageFileName:PA5-106130_EphA6_Q9UF33-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106130_EphA6_Q9UF33-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817528

Product Specific Information

Antibody detects endogenous levels of EPHA6 only when phosphorylated at Tyr978.

Target Information

EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.