Thermo Fisher Scientific GPR120 Polyclonal Antibody
GPR120 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인체 시료에 반응하며 IHC(P)에서 4–8 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS와 0.1% sodium azide 함유. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 4–8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminus of human O3FAR1 / GPR120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551395 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Monkey, Marmoset (95%)
Gibbon (89%)
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands drive conformational changes leading to G-protein signaling and downstream effects.
Negative regulation of GPCR activity plays a critical role in cellular physiology and is a key focus in drug discovery, with notable GPCR-targeted drugs such as Zyprexa and Claritin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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