Thermo Fisher Scientific GPR120 Polyclonal Antibody
Human GPR120 인식 Rabbit Polyclonal Antibody로, IHC(P)에서 1 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 및 0.1% sodium azide 포함. 4°C 단기, -20°C 장기 보관. 연구용으로만 사용.
- 카탈로그번호
- PA534034
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human O3FAR1 / GPR120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551392 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey (100%)
- Marmoset (90%)
- Bovine (80%)
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs leading to signaling via G-proteins and downstream effectors.
Ongoing studies have shown the vast series of reactions participating in the negative regulation of GPCRs. This “turn-off” activity has tremendous implications for physiological cellular action and continues to drive pharmacological research for new drug candidates.
Two GPCR-targeted blockbuster drugs, Zyprexa (Eli Lilly) and Claritin (Schering-Plough), dominate the mental health and allergy markets respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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