Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (OTI8D5), TrueMAB

Applications

Western Blot (WB)

• Assay-dependent

Flow Cytometry (Flow)

• 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The SERPINC1 gene encodes a plasma protease inhibitor belonging to the serpin superfamily. It inhibits thrombin and other activated serine proteases in the coagulation system, regulating the blood coagulation cascade.
The protein contains two functional domains:

• Heparin binding domain at the N-terminus
• Reactive site domain at the C-terminus

Inhibitory activity is enhanced by heparin. More than 120 mutations of this gene have been identified, many associated with antithrombin-III deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.