Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB
Human PARP16 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합. Lyophilized 형태로 공급되며, 재구성 및 결합 실험에 활용 가능. 고순도 Affinity Chromatography 정제 및 PBS buffer 보존. 연구용으로만 사용.
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Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C8 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human PARP16 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that supports survival of injured proliferating cells.
PARP16 belongs to the poly(ADP-ribose) polymerase (PARP) family, which includes enzymes such as PARP-1 and PARP-2 that are activated by DNA strand breaks.
This family plays roles in cell proliferation and cell death, with members sharing common partners and subcellular localizations, suggesting fine regulatory mechanisms in protein post-translational modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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