Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI4E2), TrueMAB
인간 PARP16 단백질을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태이며 PBS 버퍼에 8% 트레할로스를 포함합니다. 연구용으로 DNA 손상 반응 및 세포 생존 관련 연구에 활용됩니다.
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Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI4E2), TrueMAB
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E2 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human PARP16 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Poly(ADP-ribosyl)ation is a DNA-damage-dependent post-translational modification of histones and nuclear proteins, contributing to the survival of injured proliferating cells.
PARP16, a member of the PARP family, shares a conserved catalytic domain with PARP-1 and PARP-2, which are activated by DNA strand breaks.
The PARP family plays roles in cell proliferation and death, with members interacting and co-localizing to regulate post-translational modifications of proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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