Thermo Fisher Scientific Neurokinin 1 Receptor (NK1R) (extracellular) Polyclonal Antibody
Neurokinin 1 Receptor(NK1R) 타깃의 Rabbit Polyclonal Antibody로, Human·Mouse·Rat 반응성. WB, IHC, ICC/IF, Flow Cytometry에 적합. Lyophilized 형태로 공급되며, 항원 친화 크로마토그래피로 정제. 신경 및 스트레스 관련 연구용.
- 카탈로그번호
- ATR-001-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Neurokinin 1 Receptor (NK1R) (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CMIEWPEHPNRTYEK (aa residues 180–194 of rat NK1 receptor, 2nd extracellular loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size
- Ships as lyophilized powder at room temperature
- Upon arrival, store at -20°C
- Reconstituted solution can be stored at 4°C for up to 1 week
- For longer storage, aliquot and keep at -20°C
- Avoid multiple freeze/thaw cycles
- Centrifuge all antibody preparations before use (10,000 × g, 5 min)
Target Information
Tachykinin Receptor 1 (TACR1), also known as Neurokinin 1 Receptor, is a member of the Tachykinin Receptor subfamily. It mediates phosphatidylinositol metabolism by substance P (neurokinin 1) and is associated with depression, anxiety, and stress regulation. The receptor plays roles in behavioral responses, neuronal survival, and cardiovascular and respiratory functions. It is implicated in rheumatoid arthritis and osteoarthritis progression. Two splice variants are known. Expression is primarily in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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