Thermo Fisher Scientific BIRC3 Polyclonal Antibody
인간 BIRC3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 합성 펩타이드 면역원 기반으로 제작되었으며, Affinity Chromatography로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, PBS와 50% 글리세롤 버퍼에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BIRC3 (Accession Q13489), corresponding to amino acid residues L89–S139 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899542 |
Product Specific Information
This antibody detects endogenous levels of total BIRC3.
Target Information
The protein encoded by this gene belongs to a family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases. It inhibits apoptosis induced by serum deprivation but not by menadione exposure, a potent free radical inducer. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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