Thermo Fisher Scientific BIK Polyclonal Antibody
인간 BIK 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태, PBS/50% glycerol buffer. 세포사멸 관련 연구용으로 적합.
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Thermo Fisher Scientific BIK Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BIK (Accession Q13323), corresponding to amino acid residues D10–R60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899541 |
Product Specific Information
Antibody detects endogenous levels of total BIK.
Target Information
The Bik protein interacts with cellular and viral survival-promoting proteins such as BCL2 and Epstein-Barr virus to enhance programmed cell death. Its activity is suppressed in the presence of survival-promoting proteins, making it a likely target for antiapoptotic proteins. Bik shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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