Thermo Fisher Scientific GABRA5 Monoclonal Antibody (OTI3H7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to achieve a final concentration of about 1 mg/mL.
• For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

GABRA5 is a component of GABA, a major inhibitory neurotransmitter in the mammalian brain acting at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.