Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI7B4), TrueMAB
Human TYMP 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(P)에서 검증됨. Unconjugated 형태로 제공되며, Lyophilized 상태로 보관. Affinity chromatography로 정제되어 고순도 확보. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TYMP (Thymidine Phosphorylase), also known as platelet-derived endothelial growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine into their corresponding bases and 2-deoxyribose-1-phosphate.
It functions as a chemotactic and mitogenic factor for endothelial cells and acts as a non-heparin-binding angiogenic factor present in platelets.
TYMP is also involved in the activation of fluoropyrimidines, cytotoxic agents used in cancer therapy, converting them into active metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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