Thermo Fisher Scientific TRIM22 Monoclonal Antibody (OTI2G2), TrueMAB
인간 TRIM22 단백질을 인식하는 Mouse Monoclonal 항체로, Western blot에 최적화됨. 동결건조 형태이며 PBS 버퍼에 8% 트레할로스 포함. 재구성 시 1 mg/mL 농도로 사용 가능. 인터페론 유도 단백질 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 61–406 of human TRIM22 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) before use.
Target Information
TRIM22 is a member of the tripartite motif (TRIM) family, characterized by three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region.
It localizes to the cytoplasm and its expression is induced by interferon.
TRIM22 down-regulates transcription from the HIV-1 LTR promoter region, suggesting it mediates interferon’s antiviral effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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