Thermo Fisher Scientific Acrosin Polyclonal Antibody
Thermo Fisher Scientific의 Acrosin 폴리클로날 항체는 인간 시료에 반응하며 Western Blot, IHC, ICC/IF에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS 기반 저장용액, -20°C 보관 조건으로 안정적인 연구용 항체입니다.
- 카탈로그번호
- PA599580
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACR (Accession P10323), corresponding to amino acid residues T7–M57 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818513 |
Product Specific Information
Antibody detects endogenous levels of total Acrosin.
Target Information
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans, proacrosin first appears in the haploid spermatids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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