Thermo Fisher Scientific Phospho-TOPBP1 (Ser1159) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human TOPBP1(Accession Q92547), corresponding to amino acid residues around phosphorylated Ser1159. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TOPBP1,uniProtId:Q92547-1,ncbiNodeId:9606,antigenRange:1159,antigenLength:1522,antigenImageFileName:PA5-99577_TOPBP1_Q92547-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99577_TOPBP1_Q92547-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818510

Product Specific Information

Antibody detects endogenous levels of TOPBP1 only when phosphorylated at Ser1159.

Target Information

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.