Thermo Fisher Scientific Phospho-TOPBP1 (Ser1159) Polyclonal Antibody
TOPBP1의 Ser1159 인산화 형태를 특이적으로 검출하는 rabbit polyclonal antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 정제 및 안정적 액상 형태로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TOPBP1 (Accession Q92547), corresponding to amino acid residues around phosphorylated Ser1159 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818510 |
Product Specific Information
Antibody detects endogenous levels of TOPBP1 only when phosphorylated at Ser1159.
Target Information
This gene encodes a binding protein that interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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