Thermo Fisher Scientific alpha Adducin Polyclonal Antibody
Thermo Fisher Scientific의 alpha Adducin Polyclonal Antibody는 인간, 마우스, 랫드 등에서 반응하며 Western blot, IHC, ICC/IF, IP에 적합합니다. Rabbit IgG 기반의 비결합형 액상 항체로, 1 mg/mL 농도이며 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADD1 (Accession P35611), corresponding to amino acid residues G700–S737. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818456 |
Product Specific Information
This antibody detects endogenous levels of total ADD1.
Target Information
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein composed of related subunits produced from distinct genes but sharing similar structure. Alpha- and beta-adducin contain a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed, whereas beta-adducin is highly expressed in brain and hematopoietic tissues. Adducin binds strongly to Ca(2+)/calmodulin and serves as a substrate for protein kinases A and C. Alternative splicing produces multiple isoforms, though not all variants are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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