Thermo Fisher Scientific Relaxin 3 Polyclonal Antibody
Human Relaxin 3 단백질을 인식하는 Goat Polyclonal 항체로, Western blot 및 IHC(F) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 보존제 없이 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Pro-Relaxin-3 (Ala27–Cys142) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606330 |
Product Specific Information
- In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human mature Relaxin-3 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Relaxin 3 is a member of the Relaxin-like peptide family involved in neuropeptide signaling. It serves as a ligand for human Relaxin receptors 3 and 4, both G protein-coupled receptors. The highest expression of Relaxin 3 occurs in the brain, particularly in the pons/medulla region, with notable presence in the hippocampus and olfactory areas. Additional expression is found in the spleen, thymus, lung, and ovary. Relaxin 3 inhibits forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells expressing Relaxin receptor 3. Repeated administration of Relaxin 3 reduces plasma thyroid-stimulating hormone levels, indicating a potential role in long-term regulation of food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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