Thermo Fisher Scientific EIF2S1 Monoclonal Antibody (OTI5A5), TrueMAB
EIF2S1 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 실험에 적합합니다. Lyophilized 형태이며, PBS buffer에 trehalose 함유. 연구용으로만 사용되며, 재구성 및 conjugation 실험에 활용 가능합니다.
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Thermo Fisher Scientific EIF2S1 Monoclonal Antibody (OTI5A5), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A5 |
| Immunogen | Full length human recombinant protein of human EIF2S1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of alpha, beta, and gamma subunits.
This factor facilitates binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner, forming the 43S pre-initiation complex.
Under stress conditions, EIF2A can be phosphorylated by specific kinases, leading to inhibition of EIF2B activity and blocking guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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