Thermo Fisher Scientific Phospho-c-Jun (Thr91) Monoclonal Antibody (C-J 4C4)
Phospho-c-Jun (Thr91) 단일클론 항체로 Western blot 및 ELISA에 적합합니다. 인간과 랫트 반응성이 있으며, Mouse IgG1 형식의 Unconjugated 항체입니다. 단백질 A/G로 정제되었으며, 4°C 단기 보관 및 -20°C 장기 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| ELISA | 1:100–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C-J 4C4 |
| Immunogen | c-Jun protein phosphorylated at T91 and T93 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1016873 |
Product Specific Information
Suggested positive control: antigen standard for JUN (transient overexpression lysate).
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. It is also involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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