Thermo Fisher Scientific Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C)
Thymidine Phosphorylase 단백질을 인식하는 mouse monoclonal antibody (Clone P-GF.44C). Western blot, IHC, ICC, IP 등 다양한 응용에 적합. Human 시료 반응성, Protein A 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 16 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 | 3 publications |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 | - |
| ELISA | - | 3 publications |
| Immunoprecipitation (IP) | 1:10–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P-GF.44C |
| Immunogen | Full length human Thymidine Phosphorylase protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2210559 |
Product Specific Information
- Suggested positive control: HUVEC cells, breast carcinoma.
Target Information
Thymidine phosphorylase (also known as PD-ECGF or gliostatin) is a platelet-derived endothelial growth factor.
It catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
This enzyme is chemotactic and mitogenic for endothelial cells and acts as a non-heparin-binding angiogenic factor present in platelets.
It is also involved in the conversion of fluoropyrimidines—cytotoxic agents used in cancer therapy—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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