Thermo Fisher Scientific CDC25C Polyclonal Antibody
CDC25C 단백질을 검출하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 합성 펩타이드 면역원 기반, 액상 형태로 제공되며 -20°C 보관. 세포 분열 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDC25C (Accession P30307), corresponding to amino acid residues I190–K240 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818455 |
Product Specific Information
Antibody detects endogenous levels of total CDC25C.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved during evolution and plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. It may also suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, though the full-length nature of many remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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