Thermo Fisher Scientific PI3K p85/p55 Polyclonal Antibody
PI3K p85/p55 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC에 사용 가능. Human, Mouse, Rat 등 다양한 종에 반응. Affinity chromatography로 정제된 액상 항체이며, -20°C에서 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PI3K p85/p55 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PIK3R1 (Accession P27986), corresponding to amino acid residues E443–I493 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818451 |
Product Specific Information
This antibody detects endogenous levels of total PI3K p85/p55.
Target Information
Phosphoinositide 3-kinase (PI3K, phospho PI3K) binds to activated (phosphorylated) protein-Tyr kinases via its SH2 domain and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phospho PI3K is essential for insulin-stimulated glucose uptake and glycogen synthesis in insulin-sensitive tissues. Upon insulin stimulation, it binds to IRS-1. Growth factors and hormones trigger phosphorylation events that coordinate cell growth, cell cycle entry, migration, and survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.