Thermo Fisher Scientific ST5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ST5. Recombinant protein control fragment (Product #RP-97437). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ST5,uniProtId:P78524-1,ncbiNodeId:9606,antigenRange:463-562,antigenLength:1137,antigenImageFileName:PA5-61331_ST5_P78524-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61331_ST5_P78524-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647970

Product Specific Information

Immunogen sequence: PSSPTENGTE NQPKFGSKST LEENAYEDIV GDLPKENPYE DVDLKSRRAG RKSQQLSENS LDSLHRMWSP QDRKYNSPPT QLSLKPNSQS LRSGNWSERK

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 65%.

Target Information

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.