Thermo Fisher Scientific ST5 Polyclonal Antibody
Human ST5 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능하며 장기 보관 시 -20°C에서 안정적 유지.
- 카탈로그번호
- PA561331
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ST5. Recombinant protein control fragment (Product #RP-97437) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647970 |
Product Specific Information
Immunogen sequence:
PSSPTENGTE NQPKFGSKST LEENAYEDIV GDLPKENPYE DVDLKSRRAG RKSQQLSENS LDSLHRMWSP QDRKYNSPPT QLSLKPNSQS LRSGNWSERK
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 65%
Target Information
This gene was identified by its ability to suppress the tumorigenicity of HeLa cells in nude mice. The encoded protein contains a C-terminal region similar to the Rab3 family of small GTP-binding proteins. It preferentially binds to the SH3 domain of c-Abl kinase and regulates MAPK1/ERK2 kinase, which may contribute to its ability to reduce tumorigenic phenotype. Three alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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