Thermo Fisher Scientific GluR1 Monoclonal Antibody (N355/1)
GluR1 단백질을 검출하는 Mouse monoclonal antibody (Clone N355/1). Western blot, IHC, ICC에 적합하며 Human, Mouse, Rat 시료에 반응. Protein G 정제, PBS/glycerol buffer에 저장, -20°C 보관. For Research Use Only.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N355/1 |
| Immunogen | Fusion protein amino acids 1–389 (extracellular N-terminus) of rat GluA1/GluR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735203 |
Available Conjugated Formats
Product Specific Information
- 1 µg/mL of MA5-27694 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate using colorimetric immunoblot analysis with goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 100 kDa.
- Does not cross-react with GluR2.
- This antibody was formerly sold as clone S355-1.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting chemical signals to electrical impulses. The receptor then rapidly desensitizes and enters a transient inactive state. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed accumulation of current flux upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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