Thermo Fisher Scientific ANXA6 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat

Target Information

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are not yet fully defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways.
The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa consisting of eight 68-amino acid repeats separated by variable-length linker sequences. It is highly similar to human annexins I and II, each containing four such repeats.
Exon 21 of annexin VI is alternatively spliced, producing two isoforms differing by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI is implicated in mediating endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.