Thermo Fisher Scientific PGCA Polyclonal Antibody, Biotin
PGCA 단백질을 인식하는 Biotin 결합 토끼 폴리클로날 항체로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제되었으며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal amino acids 1042–1057 of Human PGCA. Sequence: VRTYWLLGERGCSTRG |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Guanylyl cyclases catalyze the production of cGMP from GTP and exist in soluble and membrane forms. Membrane guanylyl cyclases (A–F) act as cell-surface receptors with an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular region containing a protein kinase-like domain and a cyclase catalytic domain.
GC-A and GC-B function as receptors for natriuretic peptides (atrial and brain natriuretic peptides, respectively). NPR1 encodes a membrane-bound guanylate cyclase that serves as the receptor for both ANP and BNP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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