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Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC
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Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC

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FITC로 결합된 Rabbit Polyclonal Antibody로 Human, Mouse, Rat에서 반응합니다. Western Blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. 고순도의 Affinity Chromatography 정제 제품으로 -20°C 암소 보관이 필요합니다.

카탈로그번호
PGCB-FITC
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 06:41
Thermo Fisher Scientific PGCB-FITC PGCB Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC

Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC

Applications 및 Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
Immunohistochemistry (IHC) 1:50–1:250
Immunocytochemistry (ICC/IF) 1:50–1:250
ELISA 1:10,000
Immunoprecipitation (IP) 1:50–1:250
Immunomicroscopy (IM) 1:50–1:200

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein
Conjugate FITC
Excitation / Emission Max 498 / 517 nm
Form Liquid
Concentration 0.5–1.5 mg/mL
Purification Affinity chromatography
Storage Buffer Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA
Contains 0.02% sodium azide
Storage Conditions -20°C, store in dark
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

This gene encodes natriuretic peptide receptor B (NPR2), one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains:

  • Extracellular ligand-binding domain
  • Single membrane-spanning region
  • Intracellular protein kinase homology domain
  • Helical hinge region involved in oligomerization
  • Carboxyl-terminal guanylyl cyclase catalytic domain

The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity.
Mutations in this gene cause acromesomelic dysplasia Maroteaux type.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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