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Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC
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FITC로 결합된 Rabbit Polyclonal Antibody로 Human, Mouse, Rat에서 반응합니다. Western Blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. 고순도의 Affinity Chromatography 정제 제품으로 -20°C 암소 보관이 필요합니다.
- 판매단위
- pk
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Thermo Fisher Scientific · Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC
Thermo Fisher Scientific PGCB Polyclonal Antibody, FITC
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes natriuretic peptide receptor B (NPR2), one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains:
- Extracellular ligand-binding domain
- Single membrane-spanning region
- Intracellular protein kinase homology domain
- Helical hinge region involved in oligomerization
- Carboxyl-terminal guanylyl cyclase catalytic domain
The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity.
Mutations in this gene cause acromesomelic dysplasia Maroteaux type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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