Thermo Fisher Scientific PAOX Polyclonal Antibody
PAOX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PA5104000
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PAOX (Accession Q6QHF9), corresponding to amino acid residues A286–H336 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853331 |
Product Specific Information
Antibody detects endogenous levels of total PAOX.
Target Information
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380).
Can also oxidize N(1)-acetylspermidine to putrescine.
Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine.
Does not oxidize spermidine.
Plays an important role in the regulation of polyamine intracellular concentration and may determine cellular sensitivity to antitumor polyamine analogs (PubMed:12477380).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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