Thermo Fisher Scientific INPP5J Polyclonal Antibody
INPP5J 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human 및 Rat 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성과 재현성을 보장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human INPP5J (Accession Q15735), corresponding to amino acid residues G946–H996 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853336 |
Product Specific Information
This antibody detects endogenous levels of total INPP5J.
Target Information
INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP, PIB5PA, or INPP5, is a 1,006 amino acid cytoplasmic protein involved in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate.
It plays a role in neuronal survival and signal transduction from growth factors, neurotransmitters, and G protein-coupled receptors.
INPP5J is expressed in lung, stomach, kidney, brain, small intestine, and heart, and localizes to membrane ruffles where it may modulate inositol and phosphatidylinositol polyphosphate-binding proteins.
The gene encoding INPP5J is located on human chromosome 22 and undergoes alternative splicing to produce three isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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