Thermo Fisher Scientific ID2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ID2 protein for WB, IHC, and Flow applications. Provides strong cytoplasmic and nuclear detection. Supplied unconjugated in liquid form (1 mg/mL). Ideal for research on cell differentiation and transcription r...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within C-terminal human ID2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913576 |
Product Specific Information
- Positive Control: NCCIT cell lysates, human fetal skeletal muscle tissue, human kidney tissue, mouse colon tissue, mouse lung tissue, HepG2.
- Subcellular Location: Cytoplasm, Nucleus.
Target Information
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of various cell types including natural killer cells, erythroid precursors, CD8+ and CD4+ T-cells. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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