Thermo Fisher Scientific Ku80 Polyclonal Antibody
Ku80 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 장기 보관 가능.
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Thermo Fisher Scientific Ku80 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Ku80 (aa 51–104) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913577 |
Product Specific Information
- Positive Control: A549, HeLa, MCF-7, human liver tissue lysate, human tonsil tissue, human colon cancer tissue, human breast cancer tissue, human kidney tissue
- Subcellular Location: Nucleus, Chromosome
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and in V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer and varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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