Thermo Fisher Scientific IFNAR1 Polyclonal Antibody
인간 IFNAR1 단백질을 인식하는 Rabbit Polyclonal 항체. IHC, ICC/IF, Flow Cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human IFNAR1 aa 28–227/557 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913580 |
Product Specific Information
- Positive Control: SW620, K562
- Subcellular Location: Late endosome, Lysosome, Cell membrane
Target Information
Interferons are widely used therapeutic agents because of their antitumor and antiviral effects and their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines exert their effects by binding to the Type I Interferon Receptor (IFNAR1). Down-regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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