Thermo Fisher Scientific Human E-selectin (CD62E) Recombinant Protein
Recombinant human E-selectin (CD62E) protein with N-terminal His-tag for immunological assay controls. Expressed in E. coli and purified to >95% by SDS-PAGE. Supplied as liquid form in Tris-HCl buffer with glycerol. Ideal for research use in inflammati...
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Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Asn179–Leu557 with N-terminal His-tag |
| Tag | His-tag |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.105 mg/mL |
| Purification | Purified |
| Storage Buffer | 0.02M Tris-HCl, pH 8, with 50% glycerol, 100mM NaCl, 1mM EDTA |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human E-selectin protein with an N-terminal hexahistidine tag.
It may be used as a positive control in various immunological assays.
Target Information
Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. Leukocyte adhesion also occurs in capillaries and small venules throughout the body after inflammation onset. This process involves a cascade of adhesion receptors, including selectins and members of the immunoglobulin superfamily.
E-selectin (CD62E) is an endothelial cell-specific selectin expressed only after activation by proinflammatory cytokines such as IL-1, TNFα, and bacterial lipopolysaccharides, through an NFκB-dependent signaling cascade.
E-selectin is associated with blood vessel endothelium in various inflammatory conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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