Thermo Fisher Scientific BCL2L12 Polyclonal Antibody
BCL2L12 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunocytochemistry에 사용 가능하며, 항원은 인간 BCL2L12 유래 합성 펩타이드입니다. 액상 형태로 -20°C에서 보관합니다.
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- PA5101453
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL2L12 (Accession Q9HB09), corresponding to amino acid residues T97–A147 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850888 |
Product Specific Information
Antibody detects endogenous levels of total BCL2L12.
Target Information
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2).
The encoded protein functions as an anti-apoptotic factor, inhibiting caspases 3 and 7 in the cytoplasm.
In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes.
Overexpression has been observed in various cancers.
A pseudogene exists on chromosome 3, and alternative splicing yields multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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