Thermo Fisher Scientific BNIP2 Polyclonal Antibody
BNIP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BNIP2 (Accession Q12982), corresponding to amino acid residues F133–Y183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850887 |
Product Specific Information
Antibody detects endogenous levels of total BNIP2.
Target Information
BNIP-2 (also known as Nip2 or Nip21) shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through interaction with Cdc42GAP, BNIP-2 enhances its GTPase activity, facilitating GTP hydrolysis of Cdc42 and mediating signaling pathways involving receptor kinases, small GTPases, and apoptotic proteins.
Nix (Nip3L or Bnip3L) is closely related to BNIP-3, and both localize to mitochondria where they associate with Bcl-2 proteins.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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