Thermo Fisher Scientific B3GALT4 Polyclonal Antibody
인간 B3GALT4 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 사용 가능. Affinity chromatography로 정제된 액상 형태로 제공되며, PBS buffer와 50% glycerol 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human B3GALT4 (Accession O96024), corresponding to amino acid residues H231–A281 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850891 |
Product Specific Information
Antibody detects endogenous levels of total B3GALT4.
Target Information
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. These genes encode type II membrane-bound glycoproteins with diverse enzymatic functions, using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine).
The beta3GalT proteins contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis.
By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and four other beta3GalT genes (beta3GalT1–3, beta3GalT5). This gene is located near the ribosomal protein S18 gene and functions in ganglioseries glycolipid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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