Thermo Fisher Scientific Phospho-NFKB p65 (Ser468) Recombinant Rabbit Monoclonal Antibody (NFKBp65S468-B9)
인간 NFkB p65(Ser468) 인산화 형태를 특이적으로 인식하는 재조합 토끼 단일클론 항체. Flow Cytometry에 적합하며, 고순도 Protein A/G 정제. PBS/BSA/glycerol 저장 버퍼로 안정성 우수. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-NFKB p65 (Ser468) Recombinant Rabbit Monoclonal Antibody (NFKBp65S468-B9)
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NFKBp65S468-B9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser536 of human phospho-NFKB p65 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897134 |
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is located on chromosome 11 in humans.
NF-kB p65 (also known as RelA) belongs to the Rel family of proteins and forms part of the NF-kB complex, which heterodimerizes with p50 or p52.
Upon TNFα receptor activation, IKK phosphorylates IκB, leading to its degradation and subsequent NF-kB activation.
NF-kB p65 plays a crucial role in transcription regulation, particularly in immunoglobulin kappa gene expression in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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