ELK Biotechnology ORC1 rabbit pAb
ORC1 rabbit pAb는 인간 ORC1L 유래 펩타이드로부터 제작된 다클론성 항체입니다. WB와 ELISA에 적합하며 핵 내 ORC1 단백질 검출에 사용됩니다. DNA 복제 개시 관련 연구에 유용하며 안정적 저장(-20°C, 1년)이 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology ORC1 rabbit pAb
제품명
ORC1 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ORC1; ORC1L; PARC1; Origin recognition complex subunit 1; Replication control protein 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ORC1L (AA range: 331–380) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100, 120 kD |
| GeneID (Human) | 4998 |
| Human Swiss-Prot No | Q13415 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
The origin recognition complex (ORC) is a highly conserved six-subunit protein complex essential for the initiation of DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for assembling additional initiation factors such as Cdc6 and Mcm proteins.
The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cycle, controlled by ubiquitin-mediated proteolysis after initiation of DNA replication.
This protein is selectively phosphorylated during mitosis and interacts with MYST histone acetyltransferase 2 (MyST2/HBO1), involved in transcription silencing control. Alternatively spliced transcripts may exist.
제품 이미지
(이미지 없음)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.