ELK Biotechnology MRP-L12 rabbit pAb
MRP-L12 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 인간 및 마우스 시료에 반응하며 미토콘드리아 단백질 연구에 적합. 고순도 IgG 형태로 -20°C에서 1년 보관 가능.
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MRP-L12 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MRP-L12 rabbit pAb |
| Alternative Names | MRPL12; RPML12; 39S ribosomal protein L12; mitochondrial; L12mt; MRP-L12; 5c5-2 |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human MRPL12 (AA range: 31–80) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kDa |
| Gene ID (Human) | 6182 |
| Human Swiss-Prot No. | P52815 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Mouse |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within mitochondria. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins composing the mitoribosome vary greatly among species, making sequence homology-based recognition difficult. This gene encodes a 39S subunit protein that forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. (RefSeq, Jul 2008)
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